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In the somatic cell cycle, oscillatory activity of cyclin-cdk complexes is observed in sequential action, monitor the most important regulators of the cell cycle, inducing unidirectional transitions between phases: cyclin d and cdk4/6 are active in the g1 phase, in a bygone era as cyclin e and cdk2 are active in the late g1 and s-phase; Cyclin a and cdk2 are active in the s-phase and g2-phase of https://autismhealingcenter.com/, at that time cyclin B and cdk1 are active in the g2-phase and m-phase.